THC is the primary psychoactive component of cannabis, responsible for the “high” associated with marijuana use. It binds to CB1 receptors in the brain, leading to effects such as euphoria, altered sensory perception, and relaxation. However, THC can also cause side effects like anxiety, increased heart rate, and short-term memory impairment. For older adults, these side effects may be more pronounced, and there’s a concern about THC’s potential to contribute to cognitive decline.
CBD, on the other hand, is non-psychoactive, meaning it doesn’t produce a “high.” It’s known for its potential therapeutic benefits, including anti-inflammatory, analgesic, and anti-anxiety properties. CBD interacts with various receptors in the body, such as TRPV1 and 5-HT1A, which are involved in pain perception and mood regulation, respectively. This makes CBD an attractive option for older adults seeking relief from conditions like arthritis, chronic pain, and anxiety without the intoxicating effects of THC.
Source: https://www.mercurynews.com/2025/03/28/cbd-vs-thc-which-cannabis-compound-is-right-for-you/